The JDRF portfolio of diabetes research is among the largest in the world focused on cures and better treatments for type 1 diabetes and its complications. With funding of nearly $101 million in FY2009, representing research in more than 20 countries and including numerous human clinical trials, JDRF science is aimed at moving research discoveries into products, drugs, and treatments for people with diabetes. The major findings and developments JDRF funded over the past year, which follow, underscore the key role the organization plays in directing and catalyzing the pursuit of a cure.